Target：MYO3B

Gene Name：MYO3B

Protein Name：Myosin-IIIb (EC 2.7.11.1)

Human Gene Id：140469

Human Swiss Prot No：Q8WXR4

Mouse Swiss Prot No：Q1EG27

Immunogen：Synthesized peptide derived from human protein . at AA range: 1030-1110

Specificity：MYO3B Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：147kD

Background： This gene encodes one of the class III myosins. Myosins are ATPases, activated by actin, that move along actin filaments in the cell. This class of myosins are characterized by an amino-terminal kinase domain and shown to be present in photoreceptors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014],

Function：catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Probable actin-based motor with a protein kinase activity.,similarity:Contains 1 myosin head-like domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 2 IQ domains.,similarity:In the N-terminal section; belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family.,tissue specificity:Expressed in retina, kidney and testis.,

Subcellular Location：Cytoplasm, cytoskeleton. Cell projection, stereocilium .

Expression：Expressed in retina, kidney and testis.