Target:MYL6B
Fields:Vascular smooth muscle contraction;Tight junction;Oxytocin signaling pathway
Gene Name:MYL6B MLC1SA
Protein Name:Myosin light chain 6B (Myosin light chain 1 slow-twitch muscle A isoform) (MLC1sa) (Smooth muscle and nonmuscle myosin light chain alkali 6B)
Human Gene Id:140465
Human Swiss Prot No:P14649
Mouse Swiss Prot No:Q8CI43
Immunogen:Synthesized peptide derived from human protein . at AA range: 10-90
Specificity:MYL6B Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):22kD
Background: Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain expressed in both slow-twitch skeletal muscle and in nonmuscle tissue. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010],
Function:function:Regulatory light chain of myosin. Does not bind calcium.,similarity:Contains 3 EF-hand domains.,subunit:Myosin is an hexamer of 2 heavy chains and 4 light chains.,
Subcellular Location:cytosol,muscle myosin complex,myosin complex,unconventional myosin complex,extracellular exosome,
Expression: Brain,Ovary,Skeletal muscle,