Target：MYL6

Fields：Vascular smooth muscle contraction;Tight junction;Oxytocin signaling pathway

Gene Name：MYL6

Protein Name：Myosin light polypeptide 6

Human Gene Id：4637

Human Swiss Prot No：P60660

Mouse Gene Id：17904

Mouse Swiss Prot No：Q60605

Rat Gene Id：362816

Rat Swiss Prot No：Q64119

Immunogen：Synthesized peptide derived from the Internal region of human MYL6.

Specificity：MYL6 Polyclonal Antibody detects endogenous levels of MYL6 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：MYL6;Myosin light polypeptide 6;17 kDa myosin light chain;LC17;Myosin light chain 3;MLC-3;Myosin light chain alkali 3;Myosin light chain A3;Smooth muscle and nonmuscle myosin light chain alkali 6

Observed Band(KD)：17kD

Background： Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain that is expressed in smooth muscle and non-muscle tissues. Genomic sequences representing several pseudogenes have been described and two transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],

Function：function:Regulatory light chain of myosin. Does not bind calcium.,similarity:Contains 3 EF-hand domains.,subunit:Myosin is an hexamer of 2 heavy chains and 4 light chains.,

Subcellular Location：cytosol,brush border,membrane,myosin complex,unconventional myosin complex,extracellular matrix,vesicle,extracellular exosome,

Expression： B-cell lymphoma,Brain,Duodenum,Eye,Lung,Placenta,