Target:MY18A
Gene Name:MYO18A KIAA0216 MYSPDZ
Protein Name:Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain)
Human Gene Id:399687
Human Swiss Prot No:Q92614
Mouse Swiss Prot No:Q9JMH9
Immunogen:Synthesized peptide derived from human protein . at AA range: 1920-2000
Specificity:MY18A Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):225kD
Background:caution:The TIAF1 protein is coded in the 3'-UTR region of MYO18A.,function:May be involved in the maintenance of the stromal cell architectures required for cell to cell contact.,similarity:Contains 1 IQ domain.,similarity:Contains 1 myosin head-like domain.,similarity:Contains 1 PDZ (DHR) domain.,subcellular location:Colocalizes with actin.,subcellular location:Lacks the PDZ domain. Diffusely localized in the cytoplasm.,subunit:Homodimer. Interacts with JAK3 and actin.,
Function:caution:The TIAF1 protein is coded in the 3'-UTR region of MYO18A.,function:May be involved in the maintenance of the stromal cell architectures required for cell to cell contact.,similarity:Contains 1 IQ domain.,similarity:Contains 1 myosin head-like domain.,similarity:Contains 1 PDZ (DHR) domain.,subcellular location:Colocalizes with actin.,subcellular location:Lacks the PDZ domain. Diffusely localized in the cytoplasm.,subunit:Homodimer. Interacts with JAK3 and actin.,
Subcellular Location:Golgi apparatus . Golgi apparatus, trans-Golgi network . Golgi outpost . Cytoplasm, cytoskeleton, microtubule organizing center . Recruited to the Golgi apparatus by GOLPH3 (PubMed:19837035). Localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, which shapes dendrite morphology by functioning as sites of acentrosomal microtubule nucleation (By similarity). .; [Isoform 1]: Endoplasmic reticulum-Golgi intermediate compartment . Cytoplasm, cytoskeleton . Colocalizes with actin. .; [Isoform 2]: Cytoplasm . Lacks the PDZ domain (PubMed:12761286). Diffusely localized in the cytoplasm (PubMed:12761286). .; [Isoform 5]: Cell surface .
Expression: Amygdala,Brain,Epithelium,Liver,Peripheral blood,Platelet,Testis,