Target：MXRA5

Gene Name：MXRA5

Protein Name：Matrix-remodeling-associated protein 5 (Adhesion protein with leucine-rich repeats and immunoglobulin domains related to perlecan) (Adlican)

Human Gene Id：25878

Human Swiss Prot No：Q9NR99

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：MXRA5 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:50-300. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：311kD

Background： This gene encodes one of the matrix-remodelling associated proteins. This protein contains 7 leucine-rich repeats and 12 immunoglobulin-like C2-type domains related to perlecan. This gene has a pseudogene on chromosome Y. [provided by RefSeq, Mar 2010],

Function：developmental stage:Over-expressed in centenarians. Expression is reduced from young to old but increased from old to centenarians.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Contains 12 Ig-like C2-type (immunoglobulin-like) domains.,similarity:Contains 7 LRR (leucine-rich) repeats.,

Subcellular Location：Secreted .

Expression：Highly expressed in kidney, also detected on liver and spleen (PubMed:27599751). Expressed by proximal tubular cells of the kidney (at protein level) (PubMed:27599751). Expression highly increases during chronic kidney disease and autosomal dominant polycystic kidney disease, where is detected in cysts (PubMed:27599751).