Target:MRP-S21
Fields:Ribosome
Gene Name:MRPS21
Protein Name:28S ribosomal protein S21 mitochondrial
Human Gene Id:54460
Human Swiss Prot No:P82921
Mouse Gene Id:66292
Mouse Swiss Prot No:P58059
Immunogen:The antiserum was produced against synthesized peptide derived from human MRPS21. AA range:38-87
Specificity:MRP-S21 Polyclonal Antibody detects endogenous levels of MRP-S21 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:MRPS21;RPMS21;MDS016;28S ribosomal protein S21; mitochondrial;MRP-S21;S21mt
Observed Band(KD):11kD
Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S21P family. Pseudogenes corresponding to this gene are found on chromosomes 1p, 1q, 9p, 10p, 10q, 16q, and 17q. Available sequence data analyses identified splice varian
Function:similarity:Belongs to the ribosomal protein S21P family.,subunit:Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.,
Subcellular Location:Mitochondrion .
Expression: Brain,Cerebellum,Hematopoietic stem cell,Lung,Testis,Uterus,