Target:MRP-S18C
Fields:Ribosome
Gene Name:MRPS18C
Protein Name:28S ribosomal protein S18c mitochondrial
Human Gene Id:51023
Human Swiss Prot No:Q9Y3D5
Mouse Gene Id:68735
Mouse Swiss Prot No:Q8R2L5
Immunogen:The antiserum was produced against synthesized peptide derived from human MRPS18C. AA range:71-120
Specificity:MRP-S18C Polyclonal Antibody detects endogenous levels of MRP-S18C protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:MRPS18C;CGI-134;28S ribosomal protein S18c; mitochondrial;MRP-S18-c;Mrps18-c;S18mt-c;28S ribosomal protein S18-1, mitochondrial;MRP-S18-1
Observed Band(KD):16kD
Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondria
Function:similarity:Belongs to the ribosomal protein S18P family.,subunit:Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.,
Subcellular Location:Mitochondrion .
Expression: Brain,