Target：MRP-L40

Gene Name：MRPL40

Protein Name：39S ribosomal protein L40 mitochondrial

Human Gene Id：64976

Human Swiss Prot No：Q9NQ50

Mouse Swiss Prot No：Q9Z2Q5

Immunogen：The antiserum was produced against synthesized peptide derived from human MRPL40. AA range:101-150

Specificity：MRP-L40 Polyclonal Antibody detects endogenous levels of MRP-L40 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：MRPL40;NLVCF;URIM;39S ribosomal protein L40; mitochondrial;L40mt;MRP-L40;Nuclear localization signal-containing protein deleted in velocardiofacial syndrome;Up-regulated in metastasis

Observed Band(KD)：24kD

Background： Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome. [provided by RefSeq, Jul 2008],

Function：tissue specificity:Ubiquitous.,

Subcellular Location：Mitochondrion .

Expression：Ubiquitous.