Target:MRP-L4
Fields:Ribosome
Gene Name:MRPL4
Protein Name:39S ribosomal protein L4 mitochondrial
Human Gene Id:51073
Human Swiss Prot No:Q9BYD3
Mouse Gene Id:66163
Mouse Swiss Prot No:Q9DCU6
Immunogen:The antiserum was produced against synthesized peptide derived from human MRPL4. AA range:90-139
Specificity:MRP-L4 Polyclonal Antibody detects endogenous levels of MRP-L4 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:MRPL4;CDABP0091;CGI-28;39S ribosomal protein L4; mitochondrial;L4mt;MRP-L4
Observed Band(KD):35kD
Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified alternatively spliced variants that encode different protein isoforms. [provided by RefSeq, Jul 2008],
Function:similarity:Belongs to the ribosomal protein L4P family.,
Subcellular Location:Mitochondrion .
Expression: Leukemia,Lung,Ovary,