Target：MRP-L22
Fields：Ribosome
Gene Name：MRPL22
Protein Name：39S ribosomal protein L22 mitochondrial
Human Gene Id：29093
Human Swiss Prot No：Q9NWU5
Mouse Gene Id：216767
Mouse Swiss Prot No：Q8BU88
Rat Gene Id：287302
Rat Swiss Prot No：P0C2C0
Immunogen：The antiserum was produced against synthesized peptide derived from human MRPL22. AA range:91-140
Specificity：MRP-L22 Polyclonal Antibody detects endogenous levels of MRP-L22 protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：MRPL22;MRPL25;RPML25;HSPC158;39S ribosomal protein L22; mitochondrial;L22mt;MRP-L22;39S ribosomal protein L25, mitochondrial;L25mt;MRP-L25
Observed Band(KD)：24kD
Background： Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene. [provide
Function：similarity:Belongs to the ribosomal protein L22P family.,
Subcellular Location：Mitochondrion .
Expression： Carcinoma,Retina,Skin,Testis,Umbilical cord blood,
