Target：MRP-L12

Fields：Ribosome

Gene Name：MRPL12

Protein Name：39S ribosomal protein L12 mitochondrial

Human Gene Id：6182

Human Swiss Prot No：P52815

Mouse Gene Id：56282

Mouse Swiss Prot No：Q9DB15

Immunogen：The antiserum was produced against synthesized peptide derived from human MRPL12. AA range:31-80

Specificity：MRP-L12 Polyclonal Antibody detects endogenous levels of MRP-L12 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：MRPL12;RPML12;39S ribosomal protein L12; mitochondrial;L12mt;MRP-L12;5c5-2

Observed Band(KD)：21kD

Background： Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex. [provided by RefSeq, Jul 2008],

Function：similarity:Belongs to the ribosomal protein L12P family.,

Subcellular Location：Mitochondrion .

Expression： Muscle,Tonsil,