Target：MRP-L10
Fields：Ribosome
Gene Name：MRPL10
Protein Name：39S ribosomal protein L10 mitochondrial
Human Gene Id：124995
Human Swiss Prot No：Q7Z7H8
Mouse Swiss Prot No：Q3TBW2
Immunogen：The antiserum was produced against synthesized peptide derived from human MRPL10. AA range:211-260
Specificity：MRP-L10 Polyclonal Antibody detects endogenous levels of MRP-L10 protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：MRPL10;MRPL8;RPML8;39S ribosomal protein L10; mitochondrial;L10mt;MRP-L10;39S ribosomal protein L8, mitochondrial;L8mt;MRP-L8
Observed Band(KD)：29kD
Background： Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode two different isoforms. A pseudogene corresponding to this gene is found on chromosome 5q. [provided by RefSeq, Nov 2010],
Function：similarity:Belongs to the ribosomal protein L10P family.,subunit:Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins.,
Subcellular Location：Mitochondrion .
Expression： Pancreas,Skin,
