Target:MRGX3
Gene Name:MRGPRX3
Protein Name:Mas-related G-protein coupled receptor member X3
Human Gene Id:117195
Human Swiss Prot No:Q96LB0
Immunogen:The antiserum was produced against synthesized peptide derived from human MRGX3. AA range:99-148
Specificity:MRGX3 Polyclonal Antibody detects endogenous levels of MRGX3 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:MRGPRX3;MRGX3;SNSR1;SNSR2;Mas-related G-protein coupled receptor member X3;Sensory neuron-specific G-protein coupled receptor 1/2
Observed Band(KD):34kD
Background: This gene encodes a member of the mas-related/sensory neuron specific subfamily of G protein coupled receptors. The encoded protein may be involved in sensory neuron regulation and in the modulation of pain. [provided by RefSeq, Oct 2009],
Function:function:Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins.,similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily.,tissue specificity:Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.,
Subcellular Location:Cell membrane; Multi-pass membrane protein.
Expression:Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.