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MPP6 Polyclonal Antibody
MPP6 Polyclonal Antibody
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MPP6 Polyclonal Antibody
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经销商客户: ¥440.0
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商品描述

商品属性

Target:MPP6

Gene Name:MPP6 VAM1

Protein Name:MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1)

Human Gene Id:51678

Human Swiss Prot No:Q9NZW5

Mouse Swiss Prot No:Q9JLB0

Immunogen:Synthesized peptide derived from part region of human protein

Specificity:MPP6 Polyclonal Antibody detects endogenous levels of protein.

Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source:Polyclonal, Rabbit,IgG

Dilution:WB 1:500-2000 ELISA 1:5000-20000

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration:1 mg/ml

Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD):59kD

Background: Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).[supplied by OMIM, Mar 2008],

Function:similarity:Belongs to the MAGUK family.,similarity:Contains 1 guanylate kinase-like domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 SH3 domain.,similarity:Contains 2 L27 domains.,subunit:Interacts with CADM1 (By similarity). Interacts with the LIN7 proteins.,tissue specificity:Abundant in testis, brain, and kidney with lower levels detectable in other tissues.,

Subcellular Location:Membrane ; Peripheral membrane protein .

Expression:Abundant in testis, brain, and kidney with lower levels detectable in other tissues.

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