Target:MOGT3
Fields:Glycerolipid metabolism;Metabolic pathways;Fat digestion and absorption
Gene Name:MOGAT3 DC7 DGAT2L7 UNQ9383/PRO34208
Protein Name:2-acylglycerol O-acyltransferase 3 (EC 2.3.1.20) (EC 2.3.1.22) (Acyl-CoA:monoacylglycerol acyltransferase 3) (MGAT3) (Diacylglycerol O-acyltransferase candidate 7) (hDC7) (Diacylglycerol acyltransfera
Human Gene Id:346606
Human Swiss Prot No:Q86VF5
Immunogen:Synthesized peptide derived from human protein . at AA range: 10-90
Specificity:MOGT3 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):37kD
Background: Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA (Cheng et al., 2003 [PubMed 12618427]).[supplied by OMIM, Mar 2008],
Function:catalytic activity:Acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol.,catalytic activity:Acyl-CoA + 2-acylglycerol = CoA + diacylglycerol.,function:Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Also able to catalyze the terminal step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Has a preference toward palmitoyl-CoA and oleoyl-CoA. May be involved in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes.,pathway:Glycerolipid metabolism; triacylglycerol biosynthesis.,similarity:Belongs to the diacylglycerol acyltransferase family.,tissue specificity:Selectively expressed in the digestive system. Highly expressed in the ileum, and at lower level in jejunum, duodenum, colon, cecum and the rectum. Not expressed in the stomach and the esophagus and tr
Subcellular Location:Endoplasmic reticulum membrane ; Multi-pass membrane protein . Cytoplasm, perinuclear region .
Expression:Selectively expressed in the digestive system. Highly expressed in the ileum, and at lower level in jejunum, duodenum, colon, cecum and the rectum. Not expressed in the stomach and the esophagus and trachea. Expressed at very low level in liver.