Target:MOB1A
Fields:Hippo signaling pathway;Hippo signaling pathway - multiple species
Gene Name:MOB1B
Protein Name:MOB kinase activator 1B
Human Gene Id:92597
Human Swiss Prot No:Q7L9L4
Mouse Gene Id:68473
Mouse Swiss Prot No:Q8BPB0
Immunogen:The antiserum was produced against synthesized peptide derived from human MOL1A. AA range:101-150
Specificity:Mob1A Polyclonal Antibody detects endogenous levels of Mob1A protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:MOB1B;MOB4A;MOBKL1A;MOB kinase activator 1B;Mob1 homolog 1A;Mob1A;Mob1B;Mps one binder kinase activator-like 1A
Observed Band(KD):25kD
Background: The protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],
Function:function:Stimulates the kinase activity of STK38L.,similarity:Belongs to the MOB1/phocein family.,subunit:Binds STK38L.,
Subcellular Location:Cytoplasm . Nucleus .
Expression:Adrenal gland, bone marrow, brain, lung, placenta, prostate, salivary gland, skeletal muscle, testis, thymus, thyroid gland, uterus, colon with mucosa, fetal brain and fetal liver.