Target：NTR1

Fields：Calcium signaling pathway;Neuroactive ligand-receptor interaction

Gene Name：NTSR1

Protein Name：Neurotensin receptor type 1

Human Gene Id：4923

Human Swiss Prot No：P30989

Mouse Gene Id：18216

Mouse Swiss Prot No：O88319

Immunogen：The antiserum was produced against synthesized peptide derived from human NTR1. AA range:181-230

Specificity：NTR1 Polyclonal Antibody detects endogenous levels of NTR1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：NTSR1;NTRR;Neurotensin receptor type 1;NT-R-1;NTR1;High-affinity levocabastine-insensitive neurotensin receptor;NTRH

Observed Band(KD)：46kD

Background： Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. [provided by RefSeq, Jul 2008],

Function：function:Receptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.,online information:Neurotensin receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family.,

Subcellular Location：Cell membrane ; Multi-pass membrane protein . Membrane raft . Palmitoylation is required for localization at CAV1-enriched membrane rafts. .

Expression：Expressed in prostate (at protein level). Detected in colon and peripheral blood mononuclear cells. Detected at very low levels in brain.