Target:NTPase
Fields:Purine metabolism;Thiamine metabolism;Metabolic pathways;Nucleotide metabolism
Gene Name:NTPCR
Protein Name:Cancer-related nucleoside-triphosphatase
Human Gene Id:84284
Human Swiss Prot No:Q9BSD7
Mouse Swiss Prot No:Q9CQA9
Immunogen:The antiserum was produced against synthesized peptide derived from human C1orf57. AA range:141-190
Specificity:NTPase Polyclonal Antibody detects endogenous levels of NTPase protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:NTPCR;C1orf57;Cancer-related nucleoside-triphosphatase;NTPase;Nucleoside triphosphate phosphohydrolase
Observed Band(KD):21kD
Background: The protein encoded by this gene is a non-specific nucleoside triphosphatase that is slow-acting in vitro. This gene is overexpressed in many tumor tissues, and while it is not essential for the cell, overexpression is cytotoxic. However, the cytotoxicity is not related to its triphosphatase activity. [provided by RefSeq, Jul 2016],
Function:catalytic activity:NTP + H(2)O = NDP + phosphate.,function:Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. Hydrolyzes nucleoside diphosphates with lower efficiency.,similarity:Belongs to the THEP1 NTPase family.,subunit:Monomer.,
Subcellular Location:membrane,extracellular exosome,
Expression: Fetal brain,Skin,