Target：NT5C1A

Fields：Purine metabolism;Pyrimidine metabolism;Nicotinate and nicotinamide metabolism;Metabolic pathways;Nucleotide metabolism

Gene Name：NT5C1A

Protein Name：Cytosolic 5'-nucleotidase 1A

Human Gene Id：84618

Human Swiss Prot No：Q9BXI3

Mouse Gene Id：230718

Mouse Swiss Prot No：A3KFX0

Immunogen：The antiserum was produced against synthesized peptide derived from human NT5C1A. AA range:151-200

Specificity：NT5C1A Polyclonal Antibody detects endogenous levels of NT5C1A protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：NT5C1A;Cytosolic 5'-nucleotidase 1A;cN1A;Cytosolic 5'-nucleotidase IA;cN-I;cN-IA

Observed Band(KD)：41kD

Background： Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates (Hunsucker et al., 2001 [PubMed 11133996]).[supplied by OMIM, Mar 2008],

Function：catalytic activity:A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.,cofactor:Magnesium.,enzyme regulation:Activated by ADP.,function:Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia.,similarity:Belongs to the 5'-nucleotidase type 3 family.,tissue specificity:Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas.,

Subcellular Location：Cytoplasm.

Expression：Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas.