Target:NT-4
Fields:MAPK signaling pathway;Ras signaling pathway;PI3K-Akt signaling pathway;Neurotrophin signaling pathway
Gene Name:NTF4
Protein Name:Neurotrophin-4
Human Gene Id:4909
Human Swiss Prot No:P34130
Mouse Gene Id:78405
Mouse Swiss Prot No:Q80VU4
Rat Gene Id:25730
Rat Swiss Prot No:P34131
Immunogen:The antiserum was produced against synthesized peptide derived from human NT-4. AA range:71-120
Specificity:NT-4 Polyclonal Antibody detects endogenous levels of NT-4 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:NTF4;NTF5;Neurotrophin-4;NT-4;Neurotrophin-5;NT-5;Neutrophic factor 4
Molecular Weight(Da):22kD
Background: This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood. [provided by RefSeq, Jul 2008],
Function:function:Target-derived survival factor for peripheral sensory sympathetic neurons.,similarity:Belongs to the NGF-beta family.,tissue specificity:Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.,
Subcellular Location:Secreted.
Expression:Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.