Target:RHOJ
Fields:Salmonella infection
Gene Name:RHOJ ARHJ RASL7B RHOI TCL
Protein Name:Rho-related GTP-binding protein RhoJ (Ras-like protein family member 7B) (Tc10-like GTP-binding protein)
Human Gene Id:57381
Human Swiss Prot No:Q9H4E5
Mouse Swiss Prot No:Q9ER71
Immunogen:Synthesized peptide derived from human protein . at AA range: 30-110
Specificity:RHOJ Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):23kD
Background: This gene encodes one of the many small GTP-binding proteins in the Rho family shown to be associated with focal adhesions in endothelial cells (PMID: 21148427, 22103495). The encoded protein is activated by vascular endothelial growth factor and may regulate angiogenesis. [provided by RefSeq, Dec 2011],
Function:function:GTP-binding protein with GTPase activity. Elicits the formation of F-actin-rich structures in fibroblasts and is involved in the regulation of cell morphology.,similarity:Belongs to the small GTPase superfamily. Rho family.,subunit:Interacts with the CRIB domains of proteins such as Pak1 and Was/Wasp.,
Subcellular Location:Cell membrane ; Lipid-anchor ; Cytoplasmic side . Localization to the plasma membrane is regulated by GLUL. .
Expression:Specifically expressed in endothelial cells in different tissues, such as brain, heart, lung and liver.