Target：P311

Gene Name：NREP

Protein Name：Neuronal regeneration-related protein

Human Gene Id：9315

Human Swiss Prot No：Q16612

Mouse Gene Id：27528

Mouse Swiss Prot No：Q07475

Rat Gene Id：338475

Rat Swiss Prot No：Q80Z34

Immunogen：The antiserum was produced against synthesized peptide derived from human C5orf13. AA range:13-62

Specificity：P311 Polyclonal Antibody detects endogenous levels of P311 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：NREP;C5orf13;P311;Neuronal regeneration-related protein;Neuronal protein 3.1;Protein p311

Molecular Weight(Da)：8kD

Background：P311, also known as C5orf13 (chromosome 5 open reading frame 13), D4S114, PTZ17 or PRO1873, is a 68 amino acid cytoplasmic protein involved in cellular differentiation, neural function and axonal regeneration. Found in the granular layer of the cerebellum, P311 is expressed at lower levels in hippocampus, olfactory bulb, kidney, liver and heart and when expressed ectopically, P311 augments giloma motility. P311 is enriched in mice within the superficial cortical layers and striatum at E20 and the germinal zones at E17. Known to interact with Filamin 1, P311 regulates retinoic-acid lipid-droplet biogenesis, induces myofibroblast ameboid migration and the differentiation of fibroblasts into myofibroblasts. Ser-59 phosphorylation decreases P311 stability; the gene encoding P311 maps to human chromosome 5q22.

Function：regulation of transforming growth factor beta receptor signaling pathway,

Subcellular Location：Cytoplasm .

Expression：Expressed in lung (at protein level).