Target：PACA

Fields：cAMP signaling pathway;Neuroactive ligand-receptor interaction;Circadian entrainment;Insulin secretion;Renin secretion

Gene Name：ADCYAP1

Protein Name：Pituitary adenylate cyclase-activating polypeptide (PACAP) [Cleaved into: PACAP-related peptide (PRP-48); Pituitary adenylate cyclase-activating polypeptide 27 (PACAP-27) (PACAP27); Pituitary adenylat

Human Gene Id：116

Human Swiss Prot No：P18509

Mouse Swiss Prot No：O70176

Rat Swiss Prot No：P13589

Immunogen：Synthesized peptide derived from part region of human protein. AA range 1-38

Specificity：PACA Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 IHC 1:50-300 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：19kD

Background： This gene encodes a secreted proprotein that is further processed into multiple mature peptides. These peptides stimulate adenylate cyclase and increase cyclic adenosine monophosphate (cAMP) levels, resulting in the transcriptional activation of target genes. The products of this gene are key mediators of neuroendocrine stress responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013],

Function：function:Stimulates adenylate cyclase in pituitary cells.,similarity:Belongs to the glucagon family.,

Subcellular Location：Secreted.

Expression： Brain,Testis,