Target:PLD4
Fields:Glycerophospholipid metabolism;Ether lipid metabolism;Metabolic pathways
Gene Name:PLD4
Protein Name:Phospholipase D4
Human Gene Id:122618
Human Swiss Prot No:Q96BZ4
Mouse Gene Id:104759
Mouse Swiss Prot No:Q8BG07
Immunogen:The antiserum was produced against synthesized peptide derived from human PLD4. AA range:457-506
Specificity:PC-PLD4 Polyclonal Antibody detects endogenous levels of PC-PLD4 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000;IHC 1:50-300
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:PLD4;C14orf175;Phospholipase D4;PLD 4;Choline phosphatase 4;Phosphatidylcholine-hydrolyzing phospholipase D4
Observed Band(KD):50kD
Background:catalytic activity:A phosphatidylcholine + H(2)O = choline + a phosphatidate.,similarity:Belongs to the phospholipase D family.,similarity:Contains 2 PLD phosphodiesterase domains.,
Function:catalytic activity:A phosphatidylcholine + H(2)O = choline + a phosphatidate.,similarity:Belongs to the phospholipase D family.,similarity:Contains 2 PLD phosphodiesterase domains.,
Subcellular Location:Endoplasmic reticulum membrane ; Single-pass type II membrane protein . Golgi apparatus, trans-Golgi network membrane ; Single-pass type II membrane protein . Nucleus . Early endosome . Cytoplasmic vesicle, phagosome . Activation of microglia induces translocation of PLD4 from the nucleus to the phagosomes. .
Expression: B-cell,T-cell,