Target:PGS1
Gene Name:BGN SLRR1A
Protein Name:Biglycan (Bone/cartilage proteoglycan I) (PG-S1)
Human Gene Id:633
Human Swiss Prot No:P21810
Mouse Swiss Prot No:P28653
Rat Swiss Prot No:P47853
Immunogen:Synthesized peptide derived from human protein . at AA range: 110-190
Specificity:PGS1 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):40kD
Background: This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients. This gene and the related gene decorin are thought to be the result of a gene duplication. [provided by RefSeq, Nov 2015],
Function:function:May be involved in collagen fiber assembly.,PTM:The two attached glycosaminoglycan chains can be either chondroitin sulfate or dermatan sulfate.,similarity:Belongs to the small leucine-rich proteoglycan (SLRP) family. Class I subfamily.,similarity:Contains 12 LRR (leucine-rich) repeats.,subunit:Homodimer. Forms a ternary complex with MFAP2 and ELN.,tissue specificity:Found in several connective tissues, especially in articular cartilages.,
Subcellular Location:Secreted, extracellular space, extracellular matrix .
Expression:Found in several connective tissues, especially in articular cartilages.