Target：PGFRL

Gene Name：PDGFRL PRLTS

Protein Name：Platelet-derived growth factor receptor-like protein (PDGFR-like protein) (PDGF receptor beta-like tumor suppressor)

Human Gene Id：5157

Human Swiss Prot No：Q15198

Mouse Swiss Prot No：Q6PE55

Rat Swiss Prot No：Q5RJP7

Immunogen：Synthesized peptide derived from human protein . at AA range: 50-130

Specificity：PGFRL Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：41kD

Background： This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor. [provided by RefSeq, Jul 2008],

Function：disease:Defects in PDGFRL are associated with colorectal cancer (CRC) [MIM:114500].,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Expressed in colon, lung and liver.,

Subcellular Location：Secreted .

Expression：Expressed in colon, lung and liver.