Target:PSK2
Fields:MAPK signaling pathway
Gene Name:TAOK1
Protein Name:Serine/threonine-protein kinase TAO1
Human Gene Id:57551
Human Swiss Prot No:Q7L7X3
Mouse Gene Id:216965
Mouse Swiss Prot No:Q5F2E8
Rat Gene Id:286993
Rat Swiss Prot No:O88664
Immunogen:The antiserum was produced against synthesized peptide derived from human TAOK1. AA range:431-480
Specificity:PSK2 Polyclonal Antibody detects endogenous levels of PSK2 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:TAOK1;KIAA1361;MAP3K16;MARKK;Serine/threonine-protein kinase TAO1;Kinase from chicken homolog B;hKFC-B;MARK Kinase;MARKK;Prostate-derived sterile 20-like kinase 2;PSK-2;PSK2;Prostate-derived STE20-like kinase 2;Thousand and one
Observed Band(KD):120kD
Background:catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Phosphorylates MKK3 (By similarity). Activates the p38 MAP kinase pathway through the specific activation of the upstream MKK3 kinase.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Self-associates. Interacts with MKK3.,tissue specificity:Highly expressed in the testis, and to a lower extent also expressed in brain, placenta, colon and skeletal muscle.,
Function:catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Phosphorylates MKK3 (By similarity). Activates the p38 MAP kinase pathway through the specific activation of the upstream MKK3 kinase.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Self-associates. Interacts with MKK3.,tissue specificity:Highly expressed in the testis, and to a lower extent also expressed in brain, placenta, colon and skeletal muscle.,
Subcellular Location:Cytoplasm .
Expression:Highly expressed in the testis, and to a lower extent also expressed in brain, placenta, colon and skeletal muscle.