Target:Rag C
Fields:Autophagy - animal;mTOR signaling pathway;Shigellosis
Gene Name:RRAGC
Protein Name:Ras-related GTP-binding protein C
Human Gene Id:64121
Human Swiss Prot No:Q9HB90
Mouse Gene Id:54170
Mouse Swiss Prot No:Q99K70
Immunogen:The antiserum was produced against synthesized peptide derived from human RRAGC. AA range:302-351
Specificity:Rag C Polyclonal Antibody detects endogenous levels of Rag C protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000;IHC 1:50-300; IP 1:50-200 ELISA 2000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:RRAGC;Ras-related GTP-binding protein C;Rag C;RagC;GTPase-interacting protein 2;TIB929
Observed Band(KD):44kD
Background: This gene encodes a member of the GTR/RAG GTP-binding protein family. The encoded protein is a monomeric guanine nucleotide-binding protein which forms a heterodimer with RRAGA and RRAGB and is primarily localized to the cytoplasm. The encoded protein promotes intracellular localization of the mTOR complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012],
Function:function:Has guanine nucleotide-binding activity but weak intrinsic GTPase activity.,similarity:Belongs to the GTR/RAG GTP-binding protein family.,subcellular location:Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA.,subunit:Forms a heterodimer with RRAGA in a sequence-independent manner. Binds GTP. Interacts with NOL8 and RRAGB.,
Subcellular Location:Cytoplasm . Nucleus . Lysosome . Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA (PubMed:11073942). .
Expression: Lymph,Ovary,