Target：TDE1

Fields：Viral life cycle - HIV-1

Gene Name：SERINC3

Protein Name：Serine incorporator 3

Human Gene Id：10955

Human Swiss Prot No：Q13530

Mouse Gene Id：26943

Mouse Swiss Prot No：Q9QZI9

Immunogen：The antiserum was produced against synthesized peptide derived from human SERC3. AA range:361-410

Specificity：TDE1 Polyclonal Antibody detects endogenous levels of TDE1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SERINC3;DIFF33;TDE1;SBBI99;Serine incorporator 3;Tumor differentially expressed protein 1

Observed Band(KD)：52kD

Background：function:May be involved in cellular transformation.,PTM:N-glycosylated.,similarity:Belongs to the TDE1 family.,tissue specificity:Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues.,

Function：function:May be involved in cellular transformation.,PTM:N-glycosylated.,similarity:Belongs to the TDE1 family.,tissue specificity:Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues.,

Subcellular Location：Cell membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein .; Cytoplasm, perinuclear region . (Microbial infection) Upon HIV-1 infection, it is redirected to perinuclear region following interaction with HIV-1 Nef, excluding it from virions particles, thereby preventing subsequent antiviral defense activity (Probable). .

Expression：Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues.