Target：FRA1

Fields：Wnt signaling pathway;Osteoclast differentiation;IL-17 signaling pathway;Human T-cell leukemia virus 1 infection

Gene Name：FOSL1

Protein Name：Fos-related antigen 1

Human Gene Id：8061

Human Swiss Prot No：P15407

Mouse Gene Id：14283

Mouse Swiss Prot No：P48755

Rat Gene Id：25445

Rat Swiss Prot No：P10158

Immunogen：The antiserum was produced against synthesized peptide derived from human Fra-1. AA range:101-150

Specificity：Fra-1 Polyclonal Antibody detects endogenous levels of Fra-1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：FOSL1;FRA1;Fos-related antigen 1;FRA-1

Observed Band(KD)：43kD

Background： The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],

Function：similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. Fos subfamily.,similarity:Contains 1 bZIP domain.,subunit:Heterodimer.,

Subcellular Location：Nucleus .

Expression： Blood,Endothelial cell,Kidney,Skin,