Target:TSSK6
Gene Name:TSSK6
Protein Name:Testis-specific serine/threonine-protein kinase 6
Human Gene Id:83983
Human Swiss Prot No:Q9BXA6
Mouse Gene Id:83984
Mouse Swiss Prot No:Q925K9
Immunogen:Synthesized peptide derived from the Internal region of human TSSK 6.
Specificity:TSSK 6 Polyclonal Antibody detects endogenous levels of TSSK 6 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:TSSK6;SSTK;FKSG82;Testis-specific serine/threonine-protein kinase 6;TSK-6;TSSK-6;Testis-specific kinase 6;Cancer/testis antigen 72;CT72;Serine/threonine-protein kinase SSTK;Small serine/threonine kinase
Molecular Weight(Da):30kD
Background: This intronless gene encodes a member of the CAMK (calcium/calmodulin-dependent) serine/threonine protein kinase family. The encoded kinase has a broad expression pattern but is described as testis-specific due to effects on fertility. Male mice which lack the gene encoding a highly similar protein are sterile and have morphologically abnormal sperm. [provided by RefSeq, Jan 2012],
Function:catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,function:Required for sperm production and function. Plays a role in DNA condensation during postmeiotic chromatin remodeling.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with the heatshock proteins HSPCB, HSPA8 and HAPA1A. These interactions appear to be required for TSSK6 kinase activity.,tissue specificity:Highly expressed in testis. Expressed at lower levels in human colon, small intestine, ovary, prostate, thymus, spleen and peripheral blood leukocytes.,
Subcellular Location:nucleus,cytoplasm,
Expression:Highly expressed in testis. Expressed at lower levels in colon, small intestine, ovary, prostate, thymus, spleen and peripheral blood leukocytes.