Target：Uba5

Gene Name：UBA5

Protein Name：Ubiquitin-like modifier-activating enzyme 5

Human Gene Id：79876

Human Swiss Prot No：Q9GZZ9

Mouse Gene Id：66663

Mouse Swiss Prot No：Q8VE47

Rat Gene Id：300968

Rat Swiss Prot No：Q5M7A4

Immunogen：The antiserum was produced against synthesized peptide derived from human UBA5. AA range:281-330

Specificity：Uba5 Polyclonal Antibody detects endogenous levels of Uba5 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：UBA5;UBE1DC1;Ubiquitin-like modifier-activating enzyme 5;Ubiquitin-activating enzyme 5;ThiFP1;UFM1-activating enzyme;Ubiquitin-activating enzyme E1 domain-containing protein 1

Observed Band(KD)：45kD

Background： This gene encodes a member of the E1-like ubiquitin-activating enzyme family. This protein activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy thioester bond. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been identified on chromosome 1. [provided by RefSeq, Feb 2016],

Function：function:E1-like enzyme which activates UFM1.,similarity:Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.,

Subcellular Location：Cytoplasm . Nucleus . Endoplasmic reticulum membrane . Golgi apparatus . Localizes mainly in the cytoplasm, while it localizes to the nucleus in presence of SUMO2 (PubMed:18442052). Interaction with GABARAPL2 promotes localization to the endoplasmic reticulum membrane (PubMed:30990354). .

Expression：Widely expressed.