Target：ICAM5

Gene Name：ICAM5 TLCN TLN

Protein Name：Intercellular adhesion molecule 5 (ICAM-5) (Telencephalin)

Human Gene Id：7087

Human Swiss Prot No：Q9UMF0

Mouse Swiss Prot No：Q60625

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：ICAM5 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：101kD

Background： The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. [provided by RefSeq, Jul 2008],

Function：function:ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2).,similarity:Belongs to the immunoglobulin superfamily. ICAM family.,similarity:Contains 9 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Expressed on neurons in the most rostral segment of the mammalian brain, the telencephalon.,

Subcellular Location：Membrane; Single-pass type I membrane protein.

Expression：Expressed on neurons in the most rostral segment of the mammalian brain, the telencephalon.