Target：SRp46

Fields：Spliceosome;Herpes simplex virus 1 infection

Gene Name：SRSF8

Protein Name：Serine/arginine-rich splicing factor 8

Human Gene Id：10929

Human Swiss Prot No：Q9BRL6

Immunogen：The antiserum was produced against synthesized peptide derived from human SFRS2B. AA range:31-80

Specificity：SRp46 Polyclonal Antibody detects endogenous levels of SRp46 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SRSF8;SFRS2B;SRP46;Serine/arginine-rich splicing factor 8;Pre-mRNA-splicing factor SRP46;Splicing factor SRp46;Splicing factor; arginine/serine-rich 2B

Observed Band(KD)：32kD

Background： This gene encodes a member of a family of proteins containing a ribonucleoprotein (RNP)-type RNA binding motif and a carboxyl-terminal arginine-serine-rich (RS) domain. The encoded protein functions as a pre-mRNA splicing factor. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],

Function：function:Invovlved in pre-mRNA alternative splicing.,PTM:Phosphorylated.,similarity:Belongs to the splicing factor SR family.,similarity:Contains 1 RRM (RNA recognition motif) domain.,tissue specificity:Strongly expressed in pancreas, spleen and prostate. Weakly expressed in lung, liver and thymus.,

Subcellular Location：Nucleus .

Expression：Strongly expressed in pancreas, spleen and prostate. Weakly expressed in lung, liver and thymus.