Main Information

Target

CHMP7

Host Species

Rabbit

Reactivity

Human, Mouse

Applications

WB

MW

50kD (Calculated)

Conjugate/Modification

Unmodified

Detailed Information

Recommended Dilution Ratio

WB 1:500-2000

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Specificity

This antibody detects endogenous levels of CHMP7 at Human/Mouse

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-15°C to -25°C/1 year(Do not lower than -25°C)

Concentration

1 mg/ml

MW(Calculated)

50kD

Modification

Unmodified

Clonality

Polyclonal

Isotype

IgG

Antigen&Target Information

Immunogen:

Synthesized peptide derived from human CHMP7 AA range: 145-195

Specificity:

This antibody detects endogenous levels of CHMP7 at Human/Mouse

Gene Name:

CHMP7

Protein Name:

CHMP7

Database Link:

Organism	Gene ID	SwissProt
Human	91782;	Q8WUX9;
Mouse	105513;	Q8R1T1;

Function:

Function:Plays a role in the endosomal sorting pathway.,similarity:Belongs to the SNF7 family.,subcellular location:Diffused localization, with some punctate distribution, especially in the perinuclear area.,subunit:Interacts with CHMP4B, but not with VPS25.,

Cellular Localization:

Cytoplasm . Nucleus envelope . Nucleus envelope . Diffused localization, with some punctate distribution, especially in the perinuclear area (PubMed:16856878). Localizes to the reforming nuclear envelope on chromatin disks during late anaphase (PubMed:26040712, PubMed:28242692). .

Research Areas:

>>Endocytosis ;
>>Necroptosis