Recommended Dilution Ratio
WB 1:1000-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of human CHM4B
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Immunogen:
Synthesized peptide derived from human CHM4B AA range: 50-100
Specificity:
This antibody detects endogenous levels of human CHM4B
Gene Name:
CHMP4B C20orf178 SHAX1
Protein Name:
Charged multivesicular body protein 4b (Chromatin-modifying protein 4b) (CHMP4b) (SNF7 homolog associated with Alix 1) (SNF7-2) (hSnf7-2) (Vacuolar protein sorting-associated protein 32-2) (Vps32-2) (hVps32-2)
Cellular Localization:
Cytoplasm, cytosol . Late endosome membrane ; Peripheral membrane protein . Midbody . Nucleus envelope . Recruited to the nuclear envelope by CHMP7 during late anaphase (PubMed:26040712). Localizes transiently to the midbody arms immediately before abscission (PubMed:22422861). .
Tissue Expression:
Widely expressed. Expressed at higher level in heart and skeletal muscle. Also expressed in brain, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood lymphocytes.
Research Areas:
>>Viral life cycle - HIV-1 ;
>>Endocytosis ;
>>Necroptosis
