Main Information

Target

CHM2B

Host Species

Rabbit

Reactivity

Human, Mouse

Applications

WB

MW

23kD (Calculated)

Conjugate/Modification

Unmodified

Detailed Information

Recommended Dilution Ratio

WB 1:1000-2000

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Specificity

This antibody detects endogenous levels of human CHM2B

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-15°C to -25°C/1 year(Do not lower than -25°C)

Concentration

1 mg/ml

MW(Calculated)

23kD

Modification

Unmodified

Clonality

Polyclonal

Isotype

IgG

Antigen&Target Information

Immunogen:

Synthesized peptide derived from human CHM2B AA range: 53-103

Specificity:

This antibody detects endogenous levels of human CHM2B

Gene Name:

CHMP2B CGI-84

Protein Name:

Charged multivesicular body protein 2b (CHMP2.5) (Chromatin-modifying protein 2b) (CHMP2b) (Vacuolar protein sorting-associated protein 2-2) (Vps2-2) (hVps2-2)

Database Link:

Organism	Gene ID	SwissProt
Human	25978;	Q9UQN3;
Mouse	68942;	Q8BJF9;

Cellular Localization:

Cytoplasm, cytosol . Late endosome membrane ; Peripheral membrane protein .

Tissue Expression:

Widely expressed. Expressed in brain, heart, skeletal muscle, spleen, kidney, liver, small intestine, pancreas, lung, placenta and leukocytes. In brain, it is expressed in cerebellum, cerebral cortex, medulla, spinal chord, occipital lobe, frontal lobe, temporal lobe and putamen.

Research Areas:

>>Endocytosis ;
>>Necroptosis ;
>>Amyotrophic lateral sclerosis ;
>>Pathways of neurodegeneration - multiple diseases