Recommended Dilution Ratio
IHC 1:50-200; WB 1:500-2000; IF 1:50-200
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Specificity
This antibody detects endogenous levels of human AATC
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Immunogen:
Synthesized peptide derived from human AATC
Specificity:
This antibody detects endogenous levels of human AATC
Other Name:
Aspartate aminotransferase, cytoplasmic ;
Glutamate oxaloacetate transaminase 1 ;
Transaminase A ;
Background:
Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. [provided by RefSeq, Jul 2008],
Function:
Catalytic activity:L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.,cofactor:Pyridoxal phosphate.,miscellaneous:In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.,similarity:Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.,subunit:Homodimer.,
Cellular Localization:
Cytoplasm .
Tissue Expression:
Brain,Liver,Lung,
Research Areas:
>>Arginine biosynthesis ;
>>Alanine, aspartate and glutamate metabolism ;
>>Cysteine and methionine metabolism ;
>>Arginine and proline metabolism ;
>>Tyrosine metabolism ;
>>Phenylalanine metabolism ;
>>Phenylalanine, tyrosine and tryptophan biosynthesis ;
>>Metabolic pathways ;
>>Carbon metabolism ;
>>2-Oxocarboxylic acid metabolism ;
>>Biosynthesis of amino acids
