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β II Tubulin Polyclonal Antibody
β II Tubulin Polyclonal Antibody
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β II Tubulin Polyclonal Antibody
市场价格
经销商客户: ¥214.5
实验室客户: ¥292.5
近期销售量0 用户评价:comment rank 5()
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商品描述

商品属性

Main Information
Target
Tubulin β II
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IF
MW
50kD (Observed)
Conjugate/Modification
Unmodified
Detailed Information
Recommended Dilution Ratio
WB 1:500-2000; IF/ICC1:100-500
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Specificity
The antibody detects endogenous β II tubulin protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
MW(Observed)
50kD
Modification
Unmodified
Clonality
Polyclonal
Isotype
IgG
Antigen&Target Information
Immunogen:
Synthetic Peptide of β II Tubulin AA range: 80-130
Specificity:
The antibody detects endogenous β II tubulin protein.
Gene Name:
TUBB2A
Protein Name:
Tubulin beta-2A chain
Other Name:
Tubulin beta-2A chain
Database Link:
Organism Gene ID SwissProt
Human 7280; Q13885;
Mouse 22151; Q7TMM9;
Rat 498736; P85108;
Background:
Microtubules, key participants in processes such as mitosis and intracellular transport, are composed of heterodimers of alpha- and beta-tubulins. The protein encoded by this gene is a beta-tubulin. Defects in this gene are associated with complex cortical dysplasia with other brain malformations-5. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2015],
Function:
Function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.,similarity:Belongs to the tubulin family.,subunit:Dimer of alpha and beta chains.,
Cellular Localization:
Cytoplasm, cytoskeleton .
Tissue Expression:
High expression in brain, where it represents 30% of all beta-tubulins.
Research Areas:
>>Phagosome ;
>>Gap junction ;
>>Alzheimer disease ;
>>Parkinson disease ;
>>Amyotrophic lateral sclerosis ;
>>Huntington disease ;
>>Prion disease ;
>>Pathways of neurodegeneration - multiple diseases ;
>>Pathogenic Escherichia coli infection ;
>>Salmonella infection
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