Target：CD15

Fields：Mannose type O-glycan biosynthesis;Glycosphingolipid biosynthesis - lacto and neolacto series;Metabolic pathways

Gene Name：FUT4

Protein Name：Alpha-(1,3)-fucosyltransferase

Human Gene Id：2526

Human Swiss Prot No：P22083

Mouse Gene Id：14345

Mouse Swiss Prot No：Q11127

Rat Swiss Prot No：Q62994

Immunogen：Synthetic Peptide of CD15

Specificity：The antibody detects endogenous CD15 protein.

Formulation：PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Source：Monoclonal, Mouse

Dilution：IHC 1:200 IF 1:50-200

Purification：The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：FUT4;ELFT;FCT3A;Alpha-(1,3)-fucosyltransferase;ELAM-1 ligand fucosyltransferase;Fucosyltransferase 4;Fucosyltransferase IV;Fuc-TIV;FucT-IV;Galactoside 3-L-fucosyltransferase

Molecular Weight(Da)：46kD

Background： The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15). [provided by RefSeq, Jan 2009],

Function：caution:It is uncertain whether Met-1 or Met-126 is the initiator.,function:May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens.,online information:Fucosyltransferase 4,online information:GlycoGene database,pathway:Protein modification; protein glycosylation.,similarity:Belongs to the glycosyltransferase 10 family.,subcellular location:Membrane-bound form in trans cisternae of Golgi.,

Subcellular Location：Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Membrane-bound form in trans cisternae of Golgi.

Expression：[Isoform Short]: Expressed at low levels in bone marrow-derived mesenchymal stem cells. ; Expressed in cord blood immature promyelocytes and in peripheral blood myeloid and lymphoid cell populations.