Description:
Retroviruses are efficient tools for delivering heritable genes into the genome of dividing cells. Moloney Murine Leukemia Virus (MMLV)-based retroviral vector system is the most commonly used gene transfer vehide.Retrovirus Gag/Pol expresses the retroviral structure proteins under the control of the CMVimmediate-early promoter, The gag region encodes genes which comprise the capsid proteins; the pol region encodes the reverse transcriptase and integrase proteins.