Target：GSK3α
Fields：Chemokine signaling pathway;Dopaminergic synapse;Non-alcoholic fatty liver disease;Shigellosis
Gene Name：GSK3A
Protein Name：Glycogen synthase kinase-3 alpha
Human Gene Id：2931
Human Swiss Prot No：P49840
Mouse Gene Id：606496
Mouse Swiss Prot No：Q2NL51
Rat Gene Id：50686
Rat Swiss Prot No：P18265
Immunogen：The antiserum was produced against synthesized peptide derived from human GSK3 alpha around the phosphorylation site of Ser21. AA range:10-59
Specificity：Phospho-GSK3α (S21) Polyclonal Antibody detects endogenous levels of GSK3α protein only when phosphorylated at S21.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. Immunoprecipitation: 2-5 ug:mg lysate. ELISA: 1:20000.. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：GSK3A;Glycogen synthase kinase-3 alpha;GSK-3 alpha;Serine/threonine-protein kinase GSK3A
Observed Band(KD)：55kD
Background：glycogen synthase kinase 3 alpha(GSK3A) Homo sapiens This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. [provided by RefSeq, Oct 2011],
Function：catalytic activity:ATP + [tau protein] = ADP + [tau protein] phosphate.,function:Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer.,
Subcellular Location：mitochondrion,cytosol,beta-catenin destruction complex,postsynapse,
Expression： Brain,Eye,Foreskin,Lung,Pancreas,Platelet,Testis,
