Target：Casein Kinase Iγ1/2/3
Fields：Hedgehog signaling pathway
Gene Name：CSNK1G1/CSNK1G2/CSNK1G3
Protein Name：Casein kinase I isoform gamma-1/2/3
Human Gene Id：53944/1455/1456
Human Swiss Prot No：Q9HCP0/P78368/Q9Y6M4
Mouse Gene Id：214897/103236/70425
Rat Gene Id：64086/65278/64823
Rat Swiss Prot No：Q62761/Q62762/Q62763
Immunogen：The antiserum was produced against synthesized peptide derived from human CK-1 gamma1/2/3 around the phosphorylation site of Tyr263. AA range:229-278
Specificity：Phospho-Casein Kinase Iγ1/2/3 (Y263) Polyclonal Antibody detects endogenous levels of Casein Kinase Iγ1/2/3 protein only when phosphorylated at Y263.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：CSNK1G1;Casein kinase I isoform gamma-1;CKI-gamma 1;CSNK1G2;CK1G2;Casein kinase I isoform gamma-2;CKI-gamma 2;CSNK1G3;Casein kinase I isoform gamma-3;CKI-gamma 3
Molecular Weight(Da)：50kD
Background： This gene encodes a member of the casein kinase I gene family. This family is comprised of serine/threonine kinases that phosphorylate acidic proteins such as caseins. The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin. A mutation in this gene may be associated with non-syndromic early-onset epilepsy (NSEOE). [provided by RefSeq, Jul 2016],
Function：catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer.,
Subcellular Location：Cytoplasm.
Expression： Brain,Muscle,Pooled,
