Target：GATA-2

Gene Name：GATA2

Protein Name：Endothelial transcription factor GATA-2

Human Gene Id：2624

Human Swiss Prot No：P23769

Mouse Swiss Prot No：O09100

Immunogen：The antiserum was produced against synthesized peptide derived from human GATA2 around the phosphorylation site of Ser401. AA range:367-416

Specificity：Phospho-GATA-2 (S401) Polyclonal Antibody detects endogenous levels of GATA-2 protein only when phosphorylated at S401.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：GATA2;Endothelial transcription factor GATA-2;GATA-binding protein 2

Observed Band(KD)：50kD

Background： This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009],

Function：function:Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5'-AGATAG-3'.,sequence caution:Several sequencing errors.,similarity:Contains 2 GATA-type zinc fingers.,tissue specificity:Endothelial cells.,

Subcellular Location：Nucleus.

Expression：Endothelial cells.