Target：Pragmin

Gene Name：SGK223

Protein Name：Tyrosine-protein kinase SgK223

Human Gene Id：157285

Human Swiss Prot No：Q86YV5

Mouse Gene Id：244418

Mouse Swiss Prot No：Q571I4

Immunogen：Synthesized phospho-peptide around the phosphorylation site of human Pragmin (phospho Tyr413)

Specificity：Phospho-Pragmin (Y413) Polyclonal Antibody detects endogenous levels of Pragmin protein only when phosphorylated at Y413.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SGK223;Tyrosine-protein kinase SgK223;Sugen kinase 223

Observed Band(KD)：175kD

Background： This gene encodes an enzyme that belongs to the tyrosine protein kinase family. A similar protein in rat binds to Rho family GTPase 2 (Rnd2) and regulates neurite outgrowth via activation of Ras homolog gene family, member A (RhoA). [provided by RefSeq, Mar 2014],

Function：catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,similarity:Belongs to the protein kinase superfamily.,similarity:Contains 1 protein kinase domain.,

Subcellular Location：Cytoplasm . Cell junction, focal adhesion . Nucleus . Colocalized with NOTCH1 in the nucleus. .

Expression： Amygdala,Epithelium,Fetal brain,Spleen,