Target：Aldolase C
Fields：Glycolysis / Gluconeogenesis;Pentose phosphate pathway;Fructose and mannose metabolism;Metabolic pathways;Carbon metabolism;Biosynthesis of amino acids;HIF-1 signaling pathway
Gene Name：ALDOC
Protein Name：Fructose-bisphosphate aldolase C
Human Gene Id：230
Human Swiss Prot No：P09972
Mouse Gene Id：11676
Mouse Swiss Prot No：P05063
Rat Gene Id：24191
Rat Swiss Prot No：P09117
Immunogen：The antiserum was produced against synthesized peptide derived from the N-terminal region of human ALDOC. AA range:21-70
Specificity：Aldolase C Polyclonal Antibody detects endogenous levels of Aldolase C protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：ALDOC;ALDC;Fructose-bisphosphate aldolase C;Brain-type aldolase
Observed Band(KD)：39kD
Background： This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008],
Function：catalytic activity:D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.,miscellaneous:In vertebrates, three forms of this ubiquitous glycolytic enzyme are found, aldolase A in muscle, aldolase B in liver and aldolase C in brain.,pathway:Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.,similarity:Belongs to the class I fructose-bisphosphate aldolase family.,subunit:Homotetramer.,
Subcellular Location：mitochondrion,cytosol,cytoskeleton,extracellular exosome,
Expression： Brain,Colon,Epithelium,Eye,Uterus,
