Target:Spi-C
Gene Name:SPIC
Protein Name:Transcription factor Spi-C
Human Gene Id:121599
Human Swiss Prot No:Q8N5J4
Mouse Swiss Prot No:Q6P3D7
Immunogen:The antiserum was produced against synthesized peptide derived from human SPIC. AA range:131-180
Specificity:Spi-C Polyclonal Antibody detects endogenous levels of Spi-C protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:SPIC;Transcription factor Spi-C
Observed Band(KD):29kD
Background: The protein encoded by this gene regulates the development of red pulp macrophages, which are necessary for iron homeostasis and the recycling of red blood cells. [provided by RefSeq, Aug 2016],
Function:function:Probable transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer.,similarity:Belongs to the ETS family.,similarity:Contains 1 ETS DNA-binding domain.,subunit:Binds DNA as a monomer.,tissue specificity:Preferentially detected in fetal and adult spleen, lymph nodes and at lower levels in bone marrow and fetal liver.,
Subcellular Location:Nucleus .
Expression:Preferentially detected in fetal and adult spleen, lymph nodes and at lower levels in bone marrow and fetal liver.