Target：SPB10

Fields：Amoebiasis

Gene Name：SERPINB10 PI10

Protein Name：Serpin B10 (Bomapin) (Peptidase inhibitor 10) (PI-10)

Human Gene Id：5273

Human Swiss Prot No：P48595

Mouse Swiss Prot No：Q8K1K6

Rat Swiss Prot No：Q8K3K4

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：SPB10 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：43kD

Background： This gene is a member of the serpin peptidase inhibitor, clade B family and is found in a cluster of other similar genes on chromosome 18. The protein encoded by this gene appears to help control the regulation of protease functions during hematopoiesis. Variations in this gene may increase the risk of prostate cancer. [provided by RefSeq, Dec 2015],

Function：function:Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus.,similarity:Belongs to the serpin family.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,tissue specificity:Expressed specifically in the bone marrow.,

Subcellular Location：Nucleus. Cytoplasm. Mostly found in the nucleus.

Expression：Expressed specifically in myeloid cells and the bone marrow.