Target：SP7

Gene Name：SP7 OSX

Protein Name：Transcription factor Sp7 (Zinc finger protein osterix)

Human Gene Id：121340

Human Swiss Prot No：Q8TDD2

Mouse Swiss Prot No：Q8VI67

Immunogen：Synthesized peptide derived from human protein . at AA range: 280-360

Specificity：SP7 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：47kD

Background： This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.[provided by RefSeq, Jul 2010],

Function：function:Transcriptional activator essential for osteoblast differentiation. Binds to Sp1 and EKLF consensus sequences and to other G/C-rich sequences.,similarity:Belongs to the Sp1 C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,

Subcellular Location：Nucleus .

Expression：Restricted to bone-derived cell.