Target：SOX7

Gene Name：SOX7

Protein Name：Transcription factor SOX-7

Human Gene Id：83595

Human Swiss Prot No：Q9BT81

Mouse Swiss Prot No：P40646

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：SOX7 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：42kD

Background：SRY-box 7(SOX7) Homo sapiens This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may play a role in tumorigenesis. A similar protein in mice is involved in the regulation of the wingless-type MMTV integration site family (Wnt) pathway. [provided by RefSeq, Jul 2008],

Function：function:Transcriptional repressor. Binds to the DNA sequence 5'-AACAAT-3'.,similarity:Contains 1 HMG box DNA-binding domain.,

Subcellular Location：Nucleus . Cytoplasm .

Expression：Widely expressed in adult and fetal tissues. Present both in mesenchymal and epithelial cells in some adult tissues, including colon. Tends to be down-regulated in prostate adenocarcinomas and colorectal tumors due to promoter hypermethylation.